DR POLLEY DVM
Addressing The Testosterone Issue
"Testosterone plays a role in modulating certain behaviors such as roaming, urine marking in-doors, sexual mounting and
aggression toward other dogs (versus playful activity or dominance). Neutersol reduces the male hormone, testosterone, by
41-52% while surgical castration reduces testosterone by 95%. These behaviors may persist after either neutering method.
While testosterone plays a role in affecting certain sexually dimorphic behaviors, it is not the only factor. In fact,
the veterinary behavioral textbooks point out that there are multiple contributing factors with regard to these behaviors.
Surgical castration does not completely eliminate these behaviors. The controlled scientific studies that have assessed the
effects of surgical castration with regard to behavior have shown that most dogs continue exhibiting these behaviors. Aggression
toward humans shows little significant effect after surgical castration. Surgery can have an effect in some of these, but
is far from absolute. The FDA has reviewed the data for both surgery and Neutersol and included wording in the prescribing
information of Neutersol addressing this fact, "As with surgical castration, secondary male characteristics (roaming, marking,
aggression and mounting) may persist."
(For a complete review of the literature, visit: www.neutersol.com/testosteronefacts).